BRMS1 antibody (AA 197-246)

Catalog No. ABIN6579236

The Rabbit Polyclonal anti-BRMS1 antibody is suitable to detect BRMS1 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for BRMS1 antibody (AA 197-246) (ABIN6579236)

Target: BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRMS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BRMS1 Antibody

Binding Specificity: AA 197-246

Purpose: BRMS-1 Antibody

Specificity: BRMS-1 Polyclonal Antibody detects endogenous levels of BRMS-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human BRMS1. AA range:197-246

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BRMS1

Target: BRMS1 (Breast Cancer Metastasis Suppressor 1 (BRMS1))

Alternative Name: BRMS1

Background:

Synonyms: BRMS1, Breast cancer metastasis-suppressor 1

Background: This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines.The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Gene Name: BRMS1

Protein Name: Breast cancer metastasis-suppressor 1

Molecular Weight: 28 kDa

Gene ID: 25855

OMIM: 606259

UniProt: Q9HCU9