IGFBP6 antibody (AA 101-150)

Catalog No. ABIN6579253

This Rabbit Polyclonal antibody specifically detects IGFBP6 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for IGFBP6 antibody (AA 101-150) (ABIN6579253)

Target: IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IGFBP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IGFBP6 Antibody

Binding Specificity: AA 101-150

Purpose: IGFBP6 Antibody

Specificity: IGFBP6 Polyclonal Antibody detects endogenous levels of IGFBP6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human IGFBP6. AA range:101-150

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for IGFBP6

Target: IGFBP6 (Insulin-Like Growth Factor Binding Protein 6 (IGFBP6))

Alternative Name: IGFBP6

Background:

Synonyms: IGFBP6, IBP6, Insulin-like growth factor-binding protein 6, IBP-6, IGF-binding protein 6, IGFBP-6

Background: function:IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.,PTM:O-linked glycans consist of hexose (probably Gal), N-acetylhexosamine (probably GalNAc) and sialic acid residues. Major glycoforms consist of 8-16 monosaccharides (by homology to IGFBP6 expressed recombinantly in CHO cells).,similarity:Contains 1 IGFBP N-terminal domain.,similarity:Contains 1 thyroglobulin type-1 domain.,

Gene Name: IGFBP6

Protein Name: Insulin-like growth factor-binding protein 6

Molecular Weight: 25 kDa

Gene ID: 3489

OMIM: 146735

UniProt: P24592

Pathways: WNT Signaling, Myometrial Relaxation and Contraction