Lamin B1 antibody (AA 391-440)

Catalog No. ABIN6579290

This Rabbit Polyclonal antibody specifically detects Lamin B1 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Lamin B1 antibody (AA 391-440) (ABIN6579290)

Target: Lamin B1 (LMNB1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lamin B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Lamin B1 Antibody

Binding Specificity: AA 391-440

Purpose: Lamin B1 Antibody

Specificity: Lamin B1 Polyclonal Antibody detects endogenous levels of Lamin B1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human LMNB1. AA range:391-440

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-300 ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Lamin B1

Target: Lamin B1 (LMNB1)

Alternative Name: LMNB1

Background:

Synonyms: LMNB1, LMN2, LMNB, Lamin-B1

Background: lamin B1(LMNB1) Homo sapiens This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],

Gene Name: LMNB1

Protein Name: Lamin-B1

Molecular Weight: 66 kDa

Gene ID: 4001

OMIM: 150340

UniProt: P20700

Pathways: Apoptosis, Caspase Cascade in Apoptosis