Annexin VII antibody (AA 271-320)

Catalog No. ABIN6579329

The Rabbit Polyclonal anti-Annexin VII antibody is suitable to detect Annexin VII in samples from Human and Mouse. It has been validated for WB, IHC, ELISA and IF.

Quick Overview for Annexin VII antibody (AA 271-320) (ABIN6579329)

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Annexin VII antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-Annexin VII Antibody

Binding Specificity: AA 271-320

Purpose: Annexin VII Antibody

Specificity: Annexin VII Polyclonal Antibody detects endogenous levels of Annexin VII protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human ANXA7. AA range:271-320

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Annexin VII

Target: Annexin VII (ANXA7) (Annexin A7 (ANXA7))

Alternative Name: ANXA7

Background:

Synonyms: ANXA7; ANX7; SNX; OK/SW-cl.95; Annexin A7; Annexin VII; Annexin-7; Synexin

Background: Annexin VII is a member of the annexin family of calcium-dependent phospholipid binding proteins.The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly(A) signals. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the

Gene Name: ANXA7

Protein Name: Annexin A7

Molecular Weight: 52 kDa

Gene ID: 310

OMIM: 186360

UniProt: P20073