CD68 antibody (AA 171-220)

Catalog No. ABIN6579353

This Rabbit Polyclonal antibody specifically detects CD68 in WB and ELISA. It exhibits reactivity toward Human and Rat.

Quick Overview for CD68 antibody (AA 171-220) (ABIN6579353)

Target: CD68 (CD68 Molecule (CD68))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD68 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD68 Antibody

Binding Specificity: AA 171-220

Purpose: CD68 Antibody

Specificity: CD68 Polyclonal Antibody detects endogenous levels of CD68 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD68. AA range:171-220

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CD68

Target: CD68 (CD68 Molecule (CD68))

Alternative Name: CD68

Background:

Synonyms: CD68, Macrosialin, Gp110, CD68

Background: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms. [provided by RefSeq, Jul 2008],

Gene Name: CD68

Protein Name: Macrosialin

Molecular Weight: 37 kDa

Gene ID: 968

OMIM: 153634

UniProt: P34810