Cx40/GJA5 antibody (AA 21-70)

Catalog No. ABIN6579359

The Rabbit Polyclonal anti-Cx40/GJA5 antibody (ABIN6579359) specifically detects Cx40/GJA5 in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for Cx40/GJA5 antibody (AA 21-70) (ABIN6579359)

Target: Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cx40/GJA5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Cx40/GJA5 Antibody

Binding Specificity: AA 21-70

Purpose: Connexin-40 Antibody

Specificity: Connexin-40 Polyclonal Antibody detects endogenous levels of Connexin-40 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human GJA5. AA range:21-70

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Cx40/GJA5

Target: Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

Alternative Name: GJA5

Background:

Synonyms: GJA5, Gap junction alpha-5 protein, Connexin-40, Cx40

Background: This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008],

Gene Name: GJA5

Protein Name: Gap junction alpha-5 protein

Molecular Weight: 40 kDa

Gene ID: 2702

OMIM: 108770

UniProt: P36382

Pathways: Cell-Cell Junction Organization