Kallikrein 1 antibody (AA 81-130)

Catalog No. ABIN6579376

The Rabbit Polyclonal anti-Kallikrein 1 antibody is suitable to detect Kallikrein 1 in samples from Human, Mouse and Rat. It has been validated for WB and IHC.

Quick Overview for Kallikrein 1 antibody (AA 81-130) (ABIN6579376)

Target: Kallikrein 1 (KLK1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Kallikrein 1 Antibody

Binding Specificity: AA 81-130

Purpose: KLK1 Antibody

Specificity: KLK1 Polyclonal Antibody detects endogenous levels of KLK1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human KLK1. AA range:81-130

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Kallikrein 1

Target: Kallikrein 1 (KLK1)

Alternative Name: KLK1

Background:

Synonyms: KLK1, Kallikrein-1, Kidney/pancreas/salivary gland kallikrein, Tissue kallikrein

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen. [provided by RefSeq, Jul 2008],

Gene Name: KLK1

Protein Name: Kallikrein-1

Molecular Weight: 28 kDa

Gene ID: 3816

OMIM: 147910

UniProt: P06870

Pathways: Complement System