HSD17B4 antibody (AA 41-90)

Catalog No. ABIN6579403

This Rabbit Polyclonal antibody specifically detects HSD17B4 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for HSD17B4 antibody (AA 41-90) (ABIN6579403)

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-HSD17B4 Antibody

Binding Specificity: AA 41-90

Purpose: 17β-HSD4 Antibody

Specificity: 17β-HSD4 Polyclonal Antibody detects endogenous levels of 17β-HSD4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human HSD17B4. AA range:41-90

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:20000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for HSD17B4

Target: HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))

Alternative Name: HSD17B4

Background:

Synonyms: HSD17B4, EDH17B4, Peroxisomal multifunctional enzyme type 2, MFE-2, 17-beta-hydroxysteroid dehydrogenase 4, 17-beta-HSD 4, D-bifunctional protein, DBP, Multifunctional protein 2, MPF-2

Background: hydroxysteroid 17-beta dehydrogenase 4(HSD17B4) Homo sapiens The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014],

Gene Name: HSD17B4

Protein Name: Peroxisomal multifunctional enzyme type 2

Molecular Weight: 79 kDa

Gene ID: 3295

UniProt: P51659

Pathways: Monocarboxylic Acid Catabolic Process