CD53 antibody (AA 91-140)

Catalog No. ABIN6579460

This Rabbit Polyclonal antibody specifically detects CD53 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CD53 antibody (AA 91-140) (ABIN6579460)

Target: CD53

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD53 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CD53 Antibody

Binding Specificity: AA 91-140

Purpose: CD53 Antibody

Specificity: CD53 Polyclonal Antibody detects endogenous levels of CD53 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CD53. AA range:91-140

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CD53

Target: CD53

Alternative Name: CD53

Background:

Synonyms: CD53, MOX44, TSPAN25, Leukocyte surface antigen CD53, Cell surface glycoprotein CD53, Tetraspanin-25, Tspan-25, CD53

Background: The protein encoded byThis gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

Gene Name: CD53

Protein Name: Leukocyte surface antigen CD53

Molecular Weight: 24 kDa

Gene ID: 963

OMIM: 182160

UniProt: P19397