nectin-3 antibody (AA 311-360)

Catalog No. ABIN6579495

This Rabbit Polyclonal antibody specifically detects nectin-3 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for nectin-3 antibody (AA 311-360) (ABIN6579495)

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This nectin-3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-nectin-3 Antibody

Binding Specificity: AA 311-360

Purpose: Nectin 3 Antibody

Specificity: Nectin 3 Polyclonal Antibody detects endogenous levels of Nectin 3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human PVRL3. AA range:311-360

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for nectin-3

Target: nectin-3 (NECTIN3) (Nectin cell adhesion molecule 3 (NECTIN3))

Alternative Name: PVRL3

Background:

Synonyms: PVRL3, PRR3, Poliovirus receptor-related protein 3, CDw113, Nectin-3, CD113

Background: This gene encodes a member of the nectin family of proteins, which function as adhesion molecules at adherens junctions. This family member interacts with other nectin-like proteins and with afadin, a filamentous actin-binding protein involved in the regulation of directional motility, cell proliferation and survival. This gene plays a role in ocular development involving the ciliary body. Mutations in this gene are believed to result in congenital ocular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011],

Gene Name: PVRL3

Protein Name: Poliovirus receptor-related protein 3

Molecular Weight: 61 kDa

Gene ID: 25945

UniProt: Q9NQS3

Pathways: Cell-Cell Junction Organization