Sialoadhesin/CD169 antibody (AA 1321-1370)

Catalog No. ABIN6579529

This Rabbit Polyclonal antibody specifically detects Sialoadhesin/CD169 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for Sialoadhesin/CD169 antibody (AA 1321-1370) (ABIN6579529)

Target: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sialoadhesin/CD169 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Sialoadhesin/CD169 Antibody

Binding Specificity: AA 1321-1370

Purpose: CD169 Antibody

Specificity: CD169 Polyclonal Antibody detects endogenous levels of CD169 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human SIGLEC1. AA range:1321-1370

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for Sialoadhesin/CD169

Target: Sialoadhesin/CD169 (SIGLEC1) (Sialic Acid Binding Ig-Like Lectin 1, Sialoadhesin (SIGLEC1))

Alternative Name: SIGLEC1

Background:

Synonyms: SIGLEC1, SN, Sialoadhesin, Sialic acid-binding Ig-like lectin 1, Siglec-1, CD169

Background: This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound, however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008],

Gene Name: SIGLEC1

Protein Name: Sialoadhesin

Molecular Weight: 182 kDa

Gene ID: 6614

OMIM: 600751

UniProt: Q9BZZ2