CCR6 antibody (AA 1-50)

Catalog No. ABIN6579530

The Rabbit Polyclonal anti-CCR6 antibody (ABIN6579530) specifically detects CCR6 in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CCR6 antibody (AA 1-50) (ABIN6579530)

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCR6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CCR6 Antibody

Binding Specificity: AA 1-50

Purpose: CKR-6 Antibody

Specificity: CKR-6 Polyclonal Antibody detects endogenous levels of CKR-6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the N-terminal region of human CCR6. AA range:1-50

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for CCR6

Target: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Alternative Name: CCR6

Background:

Synonyms: CCR6, CKRL3, CMKBR6, GPR29, STRL22, C-C chemokine receptor type 6, C-C CKR-6, CC-CKR-6, CCR-6, Chemokine receptor-like 3, CKR-L3, DRY6, G-protein coupled receptor 29, GPR-CY4, GPRCY4, LARC receptor, CD196

Background: This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008],

Gene Name: CCR6

Protein Name: C-C chemokine receptor type 6

Molecular Weight: 42 kDa

Gene ID: 1235

OMIM: 601835

UniProt: P51684

Pathways: cAMP Metabolic Process