BMP15 antibody (AA 291-340)

Catalog No. ABIN6579624

This Rabbit Polyclonal antibody specifically detects BMP15 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for BMP15 antibody (AA 291-340) (ABIN6579624)

Target: BMP15 (Bone Morphogenetic Protein 15 (BMP15))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP15 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-BMP15 Antibody

Binding Specificity: AA 291-340

Purpose: BMP-15 Antibody

Specificity: BMP-15 Polyclonal Antibody detects endogenous levels of BMP-15 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human BMP15. AA range:291-340

Isotype: IgG

Application Details

Application Notes: IHC: 100-300.WB 1:500 - 1:2000. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BMP15

Target: BMP15 (Bone Morphogenetic Protein 15 (BMP15))

Alternative Name: BMP15

Background:

Synonyms: BMP15, GDF9B, Bone morphogenetic protein 15, BMP-15, Growth/differentiation factor 9B, GDF-9B

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate subunits of a disulfide-linked homodimer, or alternatively, a heterodimer, with the related protein, growth differentiation factor 9 (GDF9). This protein plays a role in oocyte maturation and follicular development, through activation of granulosa cells. Defects in this gene are the cause of ovarian dysgenesis and are associated with premature ovarian failure. [provided by RefSeq, Aug 2016],

Gene Name: BMP15

Protein Name: Bone morphogenetic protein 15

Molecular Weight: 45 kDa

Gene ID: 9210

OMIM: 300247

UniProt: O95972