GDF6 antibody (AA 311-360)

Catalog No. ABIN6579634

The Rabbit Polyclonal anti-GDF6 antibody is suitable to detect GDF6 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for GDF6 antibody (AA 311-360) (ABIN6579634)

Target: GDF6 (Growth Differentiation Factor 6 (GDF6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GDF6 Antibody

Binding Specificity: AA 311-360

Purpose: GDF-6 Antibody

Specificity: GDF-6 Polyclonal Antibody detects endogenous levels of GDF-6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GDF6. AA range:311-360

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GDF6

Target: GDF6 (Growth Differentiation Factor 6 (GDF6))

Alternative Name: GDF6

Background:

Synonyms: GDF6, GDF16, Growth/differentiation factor 6, GDF-6, Growth/differentiation factor 16

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. Mutations in this gene are associated with Klippel-Feil syndrome, microphthalmia, and Leber congenital amaurosis. [provided by RefSeq, Sep 2016],

Gene Name: GDF6

Protein Name: Growth/differentiation factor 6

Molecular Weight: 50 kDa

Gene ID: 392255

OMIM: 118100

UniProt: Q6KF10