GDF7 antibody (AA 321-370)

Catalog No. ABIN6579637

The Rabbit Polyclonal anti-GDF7 antibody (ABIN6579637) specifically detects GDF7 in WB, ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for GDF7 antibody (AA 321-370) (ABIN6579637)

Target: GDF7 (Growth Differentiation Factor 7 (GDF7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GDF7 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-GDF7 Antibody

Binding Specificity: AA 321-370

Purpose: GDF-7 Antibody

Specificity: GDF-7 Polyclonal Antibody detects endogenous levels of GDF-7 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human GDF7. AA range:321-370

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC: 1:100-1:300. ELISA: 1:10000.. IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for GDF7

Target: GDF7 (Growth Differentiation Factor 7 (GDF7))

Alternative Name: GDF7

Background:

Synonyms: GDF7; Growth/differentiation factor 7; GDF-7

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in the differentiation of tendon cells and spinal cord interneurons. A mutation in this gene may be associated with increased risk for Barrett's esophagus and esophageal adenocarcinoma. [provided by RefSeq, Sep 2016],

Gene Name: GDF7

Protein Name: Growth/differentiation factor 7

Molecular Weight: 46 kDa

Gene ID: 151449

OMIM: 604651

UniProt: Q7Z4P5

Pathways: Tube Formation