BMP6 antibody (AA 341-390)

Catalog No. ABIN6579640

The Rabbit Polyclonal anti-BMP6 antibody (ABIN6579640) specifically detects BMP6 in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for BMP6 antibody (AA 341-390) (ABIN6579640)

Target: BMP6 (Bone Morphogenetic Protein 6 (BMP6))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BMP6 Antibody

Binding Specificity: AA 341-390

Purpose: BMP-6 Antibody

Specificity: BMP-6 Polyclonal Antibody detects endogenous levels of BMP-6 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human BMP6. AA range:341-390

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:10000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for BMP6

Target: BMP6 (Bone Morphogenetic Protein 6 (BMP6))

Alternative Name: BMP6

Background:

Synonyms: BMP6, VGR, Bone morphogenetic protein 6, BMP-6, VG-1-related protein, VG-1-R, VGR-1

Background: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates a wide range of biological processes including iron homeostasis, fat and bone development, and ovulation. Differential expression of this gene may be associated with progression of breast and prostate cancer. Mutations in this gene may be associated with iron overload in human patients. [provided by RefSeq, Jul 2016],

Gene Name: BMP6

Protein Name: Bone morphogenetic protein 6

Molecular Weight: 57 kDa

Gene ID: 654

OMIM: 112266

UniProt: P22004

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process