YARS antibody (AA 451-500)

Catalog No. ABIN6579671

This Rabbit Polyclonal antibody specifically detects YARS in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for YARS antibody (AA 451-500) (ABIN6579671)

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YARS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-YARS Antibody

Binding Specificity: AA 451-500

Purpose: TyrRS Antibody

Specificity: TyrRS Polyclonal Antibody detects endogenous levels of TyrRS

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human YARS. AA range:451-500

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300 ELISA 1:10000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for YARS

Target: YARS (Yars) (Tyrosyl-tRNA Synthetase (Yars))

Alternative Name: YARS

Background:

Synonyms: Tyrosine--tRNA ligase, cytoplasmic (EC 6.1.1.1) (Tyrosyl-tRNA synthetase) (TyrRS)

Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine. [provided by RefSeq, Jul 2008],

Gene Name: YARS

Protein Name: TyrRS

Molecular Weight: 59 kDa

Gene ID: 8565

OMIM: 603623

UniProt: P54577