PLGRKT antibody (AA 1-50)

Catalog No. ABIN6579700

The Rabbit Polyclonal anti-PLGRKT antibody is suitable to detect PLGRKT in samples from Human and Rat. It has been validated for WB and IHC.

Quick Overview for PLGRKT antibody (AA 1-50) (ABIN6579700)

Target: PLGRKT (Plasminogen Receptor, C-Terminal Lysine Transmembrane Protein (PLGRKT))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLGRKT antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PLGRKT Antibody

Binding Specificity: AA 1-50

Purpose: Plasminogen receptor Antibody

Specificity: Plasminogen receptor Polyclonal Antibody detects endogenous levels of Plasminogen receptor

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human PLGRKT. AA range:1-50

Isotype: IgG

Application Details

Application Notes: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for PLGRKT

Target: PLGRKT (Plasminogen Receptor, C-Terminal Lysine Transmembrane Protein (PLGRKT))

Alternative Name: PLGRKT

Background:

Synonyms: Plasminogen receptor (KT) (Plg-R(KT))

Background: Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells. Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.

Gene Name: PLGRKT

Protein Name: Plasminogen receptor

Molecular Weight: 17 kDa

Gene ID: 55848

UniProt: Q9HBL7