FOXA1 antibody (acLys264)

Catalog No. ABIN6579719

The Rabbit Polyclonal anti-FOXA1 antibody has been validated for WB and ELISA. It is suitable to detect FOXA1 in samples from Human, Rat and Mouse.

Quick Overview for FOXA1 antibody (acLys264) (ABIN6579719)

Target: FOXA1 (Forkhead Box A1 (FOXA1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FOXA1 Antibody

Binding Specificity: AA 231-280, acLys264

Specificity:

FOXA1 (Acetyl-Lys265) Antibody detects endogenous levels of FOXA1 protein only when acetylated at Lys265.

Acetylation: H:K264/253/211, M:K264/253/213, R:K264/252/213

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using acetylated peptide. The antibody against non-acetylated peptide was removed by chromatography using corresponding non-acetylated peptide.

Immunogen: The antiserum was produced against synthesized Acetyl-peptide derived from human FOXA1 around the Acetylation site of Lys265.

Isotype: IgG

Application Details

Application Notes: WB: 1:500~1:1000 ELISA: 1:10000

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Storage: -20 °C

Storage Comment: Stable at -20°C for at least 1 year.

Target Details for FOXA1

Target: FOXA1 (Forkhead Box A1 (FOXA1))

Alternative Name: FOXA1

Background:

Synonyms: FOXA1, HNF3A, TCF3A, Hepatocyte nuclear factor 3-alpha, HNF-3-alpha, HNF-3A, Forkhead box protein A1, Transcription factor 3A, TCF-3A, FOXA2, HNF3B, TCF3B, Hepatocyte nuclear factor 3-beta, HNF-3-beta, HNF-3B, Forkhead box protein A2, Transcription factor 3B, TCF-3B, FOXA3, HNF3G, TCF3G, Hepatocyte nuclear factor 3-gamma, HNF-3-gamma, HNF-3G, Fork head-related protein FKH H3, Forkhead box protein A3, Transcription factor 3G, TCF-3G

NCBI Gene Symbol: FOXA1/FOXA2/FOXA3

Molecular Weight: 49 kDa

Gene ID: 3169, 3170, 3171

OMIM: 602294

UniProt: P55317, Q9Y261, P55318

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Carbohydrate Homeostasis