KLF1 antibody (AA 231-280)

Catalog No. ABIN6579728

The Rabbit Polyclonal anti-KLF1 antibody is suitable to detect KLF1 in samples from Human, Mouse and Rat. It has been validated for ELISA and WB.

Quick Overview for KLF1 antibody (AA 231-280) (ABIN6579728)

Target: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-KLF1 Antibody

Binding Specificity: AA 231-280

Purpose: EKLF Antibody

Specificity: EKLF Polyclonal Antibody detects endogenous levels of EKLF protein only when acetylation at K274.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: The antiserum was produced against synthesized peptide derived from human KLF1 around the non-acetylation site of Lys274. AA range:231-280

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. ELISA: 1:20000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for KLF1

Target: KLF1 (Kruppel-Like Factor 1 (erythroid) (KLF1))

Alternative Name: KLF1

Background:

Synonyms: KLF1, EKLF, Krueppel-like factor 1, Erythroid krueppel-like transcription factor, EKLF

Background: This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009],

Gene Name: KLF1

Protein Name: Krueppel-like factor 1

Molecular Weight: 38 kDa

Gene ID: 10661

OMIM: 600599

UniProt: Q13351