DYRK2 antibody (C-Term)
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- Target See all DYRK2 Antibodies
- DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
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Binding Specificity
- AA 521-549, C-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DYRK2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This Mouse Dyrk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-549 amino acids from the C-terminal region of mouse Dyrk2.
- Clone
- RB34467
- Isotype
- Ig Fraction
- Top Product
- Discover our top product DYRK2 Primary Antibody
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anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 105-135), (N-Term) antibody
DYRK2 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB3008 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibodyDYRK2 Reactivity: Human WB, ELISA, IF Host: Mouse Monoclonal 6E2 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibodyDYRK2 Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 2F9 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 502-601) antibodyDYRK2 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibodyDYRK2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 2F9 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 1-100) antibodyDYRK2 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 4G11 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 429-528) antibodyDYRK2 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (C-Term) antibodyDYRK2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (AA 105-135) antibodyDYRK2 Reactivity: Human WB Host: Mouse Monoclonal 492CT4-2-4 unconjugated
anti-Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2) (C-Term) antibodyDYRK2 Reactivity: Human WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:2000. WB: 1:1000. WB: 1:8000. IHC-P: 1:100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Mouse Dyrk2 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Expiry Date
- 6 months
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- Target
- DYRK2 (Dual-Specificity tyrosine-(Y)-phosphorylation Regulated Kinase 2 (DYRK2))
- Alternative Name
- Dyrk2 (DYRK2 Products)
- Background
- Role in the regulation of cellular growth and/or development. Regulates TP53 by phosphorylation on Ser-46 to induce apoptosis in response to DNA damage, functioning downstream of ATM. Inactivates GYS1 by phosphorylation at Ser-641, and potentially also a second phosphorylation site, thus regulating glycogen synthesis. Phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates (By similarity).
- Molecular Weight
- 66556
- Gene ID
- 69181
- NCBI Accession
- NP_001014412
- UniProt
- Q5U4C9
- Pathways
- Regulation of Carbohydrate Metabolic Process
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