PAX6 antibody

Catalog No. ABIN659068

This Mouse Monoclonal antibody specifically detects PAX6 in WB and IF. It exhibits reactivity toward Human.

Quick Overview for PAX6 antibody (ABIN659068)

Target: PAX6 (Paired Box 6 (PAX6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAX6 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 193CT15-2-2

Product Details anti-PAX6 Antibody

Predicted Reactivity: B, M

Purification: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This PAX6 Monoclonal antibody was raised using purified His-tagged recombinant human PAX6.

Isotype: IgM kappa

Application Details

Application Notes: IF: 1:10~50. WB: 1:500~16000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PAX6

Target: PAX6 (Paired Box 6 (PAX6))

Alternative Name: PAX6

Background: This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA, and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding either the same or different isoform have been found for this gene. [provided by RefSeq].

Molecular Weight: 46683

Gene ID: 5080

NCBI Accession: NP_000271, NP_001121084, NP_001245393, NP_001245394, NP_001595

UniProt: P26367

Pathways: Peptide Hormone Metabolism, Carbohydrate Homeostasis