Urm1 antibody

Catalog No. ABIN659088

The Mouse Monoclonal anti-Urm1 antibody (Clone 182CT27-2-2) (ABIN659088) specifically detects Urm1 in WB. The antibody is reactive with Human samples.

Quick Overview for Urm1 antibody (ABIN659088)

Target: Urm1 (Ubiquitin Related Modifier 1 (Urm1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Urm1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 182CT27-2-2

Product Details anti-Urm1 Antibody

Purification: This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Immunogen: This URM1 monoclonal antibody is generated from mouse immunized with URM1 recombinant protein.

Isotype: IgM kappa

Application Details

Application Notes: WB: 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for Urm1

Target: Urm1 (Ubiquitin Related Modifier 1 (Urm1))

Alternative Name: URM1

Background: Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. May also act as an ubiquitin-like protein that is covalently conjugated to other proteins, the relevance of such function is however unclear in vivo.

Molecular Weight: 11380

Gene ID: 81605

NCBI Accession: NP_001129419, NP_112176

UniProt: Q9BTM9