NONO
Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig
WB, IF
Host: Rabbit
Polyclonal
unconjugated
Application Notes
Optimal dilution of the NONO antibody should be determined by the researcher.\. Western blot: 0.5-1 μg/mL,ICC (FFPE): 1-2 μg/mL,FACS: 1-3 μg/10^6 cells
Restrictions
For Research Use only
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Storage
-20 °C
Storage Comment
After reconstitution, the NONO antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Non-POU domain-containing octamer-binding protein is a protein that in humans is encoded by the NONO gene. This gene encodes an RNA-binding protein which plays various roles in the nucleus, including transcriptional regulation and RNA splicing. A rearrangement between this gene and the transcription factor E3 gene has been observed in papillary renal cell carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes exist on Chromosomes 2 and 16.