Cyclin D2 antibody

Catalog No. ABIN6654335

The Mouse Monoclonal anti-Cyclin D2 antibody (Clone CCND2-2620) (ABIN6654335) specifically detects Cyclin D2 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Cyclin D2 antibody (ABIN6654335)

Target: Cyclin D2 (CCND2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cyclin D2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CCND2-2620

Product Details anti-Cyclin D2 Antibody

Purification: Purified

Purity: Protein G affinity chromatography

Immunogen: Recombinant human protein was used as the immunogen for the Cyclin D2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Cyclin D2 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Cyclin D2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for Cyclin D2

Target: Cyclin D2 (CCND2)

Alternative Name: Cyclin D2 / CCND2

Background: Cyclins are a family of proteins that control how cells proceed through the multi-step cycle of cell division. Cyclin D2 helps to regulate a step in the cycle called the G1-S transition, in which the cell moves from the G1 phase, when cell growth occurs, to the S phase, when the cell's DNA is copied (replicated) in preparation for cell division. Cyclin D2's role in the cell division cycle makes it a key controller of the rate of cell growth and division (proliferation) in the body.

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases