The Rabbit Monoclonal anti-Mammaglobin A antibody (Clone MGB-2123R) (ABIN6654458) specifically detects Mammaglobin A in IHC (p).
The antibody is reactive with Human samples.
SCGB2A2
Reactivity: Human
WB, IHC
Host: Rabbit
Monoclonal
unconjugated
Application Notes
Optimal dilution of the recombinant Mammaglobin antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Preservative
Azide free
Storage
4 °C,-20 °C
Storage Comment
Store the recombinant Mammaglobin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
Mammaglobin A (SCGB2A2)
(Secretoglobin, Family 2A, Member 2 (SCGB2A2))
Alternative Name
Mammaglobin A / SCGB2A2
Background
Mammaglobin, also called Secretoglobin family 2A member 2, or SCGB2A2, is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues. Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.