Calretinin antibody (AA 23-242)

Catalog No. ABIN6654490

The Mouse Monoclonal anti-Calretinin antibody has been validated for IHC (p). It is suitable to detect Calretinin in samples from Human.

Quick Overview for Calretinin antibody (AA 23-242) (ABIN6654490)

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Calretinin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CALB2-2603

Product Details anti-Calretinin Antibody

Binding Specificity: AA 23-242

Purification: Purified

Purity: Protein G affinity

Immunogen: A portion of amino acids 23-242 from the human protein was used as the immunogen for the Calretinin antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Calretinin antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the Calretinin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for Calretinin

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Alternative Name: Calbindin 2 / CALB2 / Calretinin

Background: It recognizes a protein of about 29 kDa, which is identified as Calretinin (also known as Calbindin 2). Calretinin is a vitamin D-dependent calcium-binding protein involved in calcium signaling. It is present in subsets of neurons throughout the brain and spinal chord, including sensory ganglia. Antibody to calretinin is useful in differentiating mesothelioma from adenocarcinomas of the lung. It also aids in differentiating adrenal cortical neoplasms from pheochromocytomas.