IL7R antibody (AA 21-236)

Catalog No. ABIN6654532

The Mouse Monoclonal anti-IL7R antibody has been validated for IHC (p). It is suitable to detect IL7R in samples from Human.

Quick Overview for IL7R antibody (AA 21-236) (ABIN6654532)

Target: IL7R (Interleukin 7 Receptor (IL7R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL7R antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IL7R-2751

Product Details anti-IL7R Antibody

Binding Specificity: AA 21-236

Purification: Purified

Purity: Protein G affinity chromatography

Immunogen: A portion of amino acids 21-236 from the human protein was used as the immunogen for the CD127 antibody.

Isotype: IgG2c kappa

Application Details

Application Notes: Optimal dilution of the CD127 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 2-4 μg/mL for 30 min at RT,Prediluted IHC only format: incubate for 30 min at RT (1)

Restrictions: For Research Use only

Handling

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the CD127 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Alternative Name: IL7R / CD127

Background: The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID).

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size