SAT1 antibody

Catalog No. ABIN6654647

The Mouse Monoclonal anti-SAT1 antibody (Clone CPTC-SAT1-3) (ABIN6654647) specifically detects SAT1 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for SAT1 antibody (ABIN6654647)

Target: SAT1 (Spermidine/spermine N1-Acetyltransferase 1 (SAT1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SAT1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CPTC-SAT1-3

Product Details anti-SAT1 Antibody

Purification: Purified

Purity: Protein G affinity chromatography

Immunogen: Recombinant human protein was used as the immunogen for this SAT1 antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the SAT1 antibody should be determined by the researcher.\. IHC (FFPE): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the SAT1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for SAT1

Target: SAT1 (Spermidine/spermine N1-Acetyltransferase 1 (SAT1))

Alternative Name: SAT1 / Spermidine/spermine N(1)-acetyltransferase 1

Background: Spermidine/spermine N1-acetyltransferase 1 (SAT1 or SSAT1) is the key regulatory enzyme in the catabolism of polyamines, catalyzing acetylation of spermidine or spermine to generate N1-acetyl spermidine or N1-acetyl spermine, and N1, N12-diacetylspermine. The cellular level of SAT1 is normally extremely low, but it is induced rapidly by a variety of stimuli, including polyamines, polyamine analogs, toxic chemicals, certain drugs, and growth factors. Downregulation of SAT1 has been reported in Epstein-Barr virus positive Burkitt's lymphoma cells.