SAT1 antibody
Quick Overview for SAT1 antibody (ABIN6654647)
Target
See all SAT1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- SAT1 Antibody / Spermidine/spermine N(1)-acetyltransferase 1
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Purification
- Protein G affinity chromatography
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Immunogen
- Recombinant human protein was used as the immunogen for this SAT1 antibody.
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Isotype
- IgG2a, kappa
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Application Notes
- Optimal dilution of the SAT1 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store the SAT1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- SAT1 (Spermidine/spermine N1-Acetyltransferase 1 (SAT1))
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Alternative Name
- SAT1
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Background
- Spermidine/spermine N1-acetyltransferase 1 (SAT1 or SSAT1) is the key regulatory enzyme in the catabolism of polyamines, catalyzing acetylation of spermidine or spermine to generate N1-acetyl spermidine or N1-acetyl spermine, and N1, N12-diacetylspermine. The cellular level of SAT1 is normally extremely low, but it is induced rapidly by a variety of stimuli, including polyamines, polyamine analogs, toxic chemicals, certain drugs, and growth factors. Downregulation of SAT1 has been reported in Epstein-Barr virus positive Burkitt's lymphoma cells.
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UniProt
- P21673
Target
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