Calm1, Calm2, Calm3 antibody

Catalog No. ABIN6655038

Supplier Product No.: 200-301-p25

This Mouse Monoclonal antibody specifically detects Calm1, Calm2, Calm3 in WB and ELISA.

Quick Overview for Calm1, Calm2, Calm3 antibody (ABIN6655038)

Target: Calm1, Calm2, Calm3

Reactivity: Please inquire

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 6D4

Product Details

Supplier Product No.: 200-301-p25

Supplier: Rockland

Purpose: Calmodulin Antibody

Cross-Reactivity (Details): This product reacts with human, mouse, and rabbit.

Purification: Anti-Calmodulin antibody was purified from mouse ascites by protein A chromatography.

Immunogen: Calmodulin antibody was produced in mice by repeated immunizations with a preparation of purified calmodulin from Dictyostelium discoideum conjugated to KLH.

Isotype: IgG1

Application Details

Application Notes:

ELISA_Dilution: 1:5000

Western_Blot_Dilution: 0.5 μg/mL

Comment:

Anti-Calmodulin has been tested in Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~16.8 kDa corresponding to the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Neutral PBS

Reconstitution_Volume: 1.0 mL

Buffer:

Buffer: 1.2 % sodium acetate

Stabilizer: 2 mg BSA

Preservative: 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details

Target: Calm1, Calm2, Calm3

Background:

Synonyms: CALM, CAM, CAM1, CAM2, CAMB, CALML2, CAM3, CAMC, CAMIII

Background: Calmodulin is the archetype of the family of calcium-modulated proteins of which nearly 20 members have been found. Calmodulin contains 149 amino acids and has 4 calcium-binding domains. Its functions include roles in growth and the cell cycle as well as in signal transduction and the synthesis and release of neurotransmitters. Three calmodulin genes (CALM1, CALM2, and CALM3) map to chromosomes 14q24-q31, 2p21.1-p21.3, and 19q13.2-q13.3, respectively. This antibody is suitable for researchers interested in cardiovascular diseases, neurodegenerative diseases, autoimmune diseases, Cancer research, Developmental Signaling, Inflammatory Signaling, Cytoskeletal Signaling, GPCR signaling, AKT Signaling, and MAK Kinase Signaling.

Gene Name: CALM1, CALM2, CALM3

Gene ID: 801

NCBI Accession: NP_001734

UniProt: P62158