DDC antibody

Catalog No. ABIN6655051

Product Details anti-DDC Antibody

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Reactivity: Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DDC antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Rat (Rattus)

Cross-Reactivity (Details): Cross reactivity bovine expect, reactivity with DOPA Decarboxylase from other species has not been determined.

Purification: Anti-DOPA Decarboxylase antibody is directed against DOPA Decarboxylase. Anti-DOPA Decarboxylase antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Anti-DOPA Decarboxylase antibody recognizes DOPA Decarboxylase from rat sources.

Immunogen:

Immunogen: Anti-DOPA Decarboxylase Antibody was produced in rabbit by repeated immunizations with purified from inclusion bodies and SDS denatured recombinant bovine aromatic DOPA decarboxylase expressed in E. coli.

Immunogen Type: Recombinant Protein

Isotype: IgG

Application Details

Application Notes:

Application Note: Anti-DOPA Decarboxylase Antibody is suitable for use in ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 55 kDa in size corresponding to the DDC proteins in the appropriate cell lysate or extract.

ELISA Dilution: 1:10,000

Western Blot Dilution: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Target Details for DDC

Target: DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

Alternative Name: DOPA Decarboxylase (DDC Products)

Synonyms: AADC antibody, wu:fa56d05 antibody, wu:fd59h03 antibody, wu:fk20h01 antibody, zgc:65801 antibody, zgc:76929 antibody, Ddc antibody, DdcDv antibody, Dvir\\GJ17995 antibody, GJ17995 antibody, dvir_GLEANR_2561 antibody, Aadc antibody, 5-HT antibody, CG10697 antibody, DDC antibody, DdcDm antibody, Dmel\\CG10697 antibody, ddc antibody, fDDC antibody, l(2)37Bl antibody, l(2)37Ch antibody, l(2)k02104 antibody, dopa decarboxylase antibody, Dopa-decarboxylase antibody, dopa decarboxylase (aromatic L-amino acid decarboxylase) antibody, Dopa decarboxylase antibody, dopa decarboxylase L homeolog antibody, DDC antibody, ddc antibody, Ddc antibody, Dvir\Ddc antibody, ddc.L antibody

Background:

Synonyms: Aromatic-L-amino-acid decarboxylase, DDC, AADC

Background: DOPA Decarboxylase Antibody detects DOPA decarboxylase (aromatic L-amino acid decarboxylase, AADC, DDC) which catalyzes the second reaction in the biosynthesis of catecholamines and serotonin. It is also involved in the biosynthesis of trace amines. DDC antibodies can therefore be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse. Anti-DOPA Decarboxylase Antibody is ideal for investigators involved in neurological disorders and, more generally in Neuroscience.

Gene Name: DDC

Gene ID: 280762

NCBI Accession: NP_776332

UniProt: P27718

Pathways: Dopaminergic Neurogenesis