SOX4 antibody

Catalog No. ABIN6655256

Supplier Product No.: 100-401-v96

This anti-SOX4 antibody is a Rabbit Polyclonal antibody detecting SOX4 in WB and ELISA. Suitable for Human.

Quick Overview for SOX4 antibody (ABIN6655256)

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOX4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SOX4 Antibody

Supplier Product No.: 100-401-v96

Supplier: Rockland

Purpose: SOX4 Antibody

Cross-Reactivity (Details): Cross reactivity with SOX4 from other species not tested.

Purification: Anti-SOX4 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

Sterility: Sterile filtered

Immunogen: Anti-SOX4 Antibody was produced in rabbits by repeated immunizations with two different synthetic peptides of human SOX4 containing an amino acid sequence from the N-terminus and C-terminus of the protein respectively.

Isotype: IgG

Application Details

Application Notes:

ELISA_Dilution: 1:100 - 1:1,000

Western_Blot_Dilution: 1:4,000

Comment:

Anti-SOX4 Antibody has been tested by ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 47 kDa in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: None

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for SOX4

Target: SOX4 (SRY (Sex Determining Region Y)-Box 4 (SOX4))

Alternative Name: SOX4

Background:

Synonyms: Transcription factor SOX-4, EVI16, Sex determining region Y box 4

Background: SOX4 belongs to the SOX family of transcription factors. These transcription factors are characterized by the conserved HMG (high mobility group) DNA binding domain and are involved in embryonic development. SOX4 has been shown to be important for the development of the cardiac outflow tract and of the internal nervous system. SOX 4 may also be involved in the apoptosis pathway were it can either lead to cell death or to tumorigenesis, and has been associated with several human cancer types. Anti-SOX4 Antibody is ideal for research in Cell Differentiation and Development, Gene Expression, Apoptosis and Cancer.

Gene Name: SOX4

Gene ID: 6659

NCBI Accession: NP_003098

UniProt: Q06945