PHF8 antibody

Catalog No. ABIN6655278

Product Details anti-PHF8 Antibody

Target: PHF8 (PHD Finger Protein 8 (PHF8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHF8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Anti-PHF8 Antibody was purified by affinity purification. This product reacts with human PHF8.  Cross reactivity with PHF8 from species other than human is not known.

Immunogen:

Immunogen: Anti-PHF8 Antibody was produced in rabbits by repeated immunizations with three different synthetic peptides containing sequences from human PHF8.

Immunogen Type: Peptide

Isotype: IgG

Application Details

Application Notes:

Application Note: Anti-PHF8 Antibody is suitable for ELISA and Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 115 kDa in the appropriate cell lysate or extract.

ELISA Dilution: 1:100 - 1:500

Western Blot Dilution: 1:1,000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M Sodium Phosphate, 0.25 M Sodium Chloride, pH 7.2

0.05 % (w/v) Sodium Azide and 0.05 % ProClin 300/p>

Stabilizer: None

Preservative: ProClin, Sodium azide

Precaution of Use: This product contains Sodium azide and ProClin: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Storage: RT,4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Target Details for PHF8

Target: PHF8 (PHD Finger Protein 8 (PHF8))

Alternative Name: PHF8 (PHF8 Products)

Synonyms: 9830141C09Rik antibody, mKIAA1111 antibody, JHDM1F antibody, MRXSSD antibody, ZNF422 antibody, RGD1561065 antibody, zPHF8 antibody, PHD finger protein 8 antibody, Phf8 antibody, PHF8 antibody, phf8 antibody

Background:

Synonyms: Histone lysine demethylase PHF8, PHD finger protein 8, ZNF422

Background: PHD finger protein 8 is a jumonji domain containing protein. Like other members of the jumonji family, PHF8 may therefore play a role in histone demethylation. Mutations in PHF8 lead to Siderius type X-linked mental retardation (MRXSSD), a mild to borderline type of mental retardation. Anti-PHF8 Antibody is ideal for research in Epigenetics and Neuroscience.

Gene Name: PHF8

Gene ID: 23133

NCBI Accession: NP_001171825

UniProt: Q9UPP1