SETD7 antibody

Catalog No. ABIN6655577

Supplier Product No.: 100-401-v83

This anti-SETD7 antibody is a Rabbit Polyclonal antibody detecting SETD7 in WB. Suitable for Human.

Quick Overview for SETD7 antibody (ABIN6655577)

Target: SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SETD7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SETD7 Antibody

Supplier Product No.: 100-401-v83

Supplier: Rockland

Purpose: SET9 Antibody

Cross-Reactivity (Details): Cross reactivity with Set8 from species other than human not tested.

Purification: Anti-Set9 Antibody is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration.

Sterility: Sterile filtered

Immunogen: Anti-SET9 Antibody was produced in rabbits by repeated immunizations with a recombinant protein of human Set9.

Isotype: IgG

Application Details

Application Notes: Optional[Neutralization_Dilution]: 1:1,000

Comment:

Anti-SET9 Antibody has been tested by Western Blots. Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 50 kDa in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: None

Stabilizer: None

Preservative: 0.05 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for SETD7

Target: SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))

Alternative Name: Set9

Background:

Synonyms: Histone-lysine N-methyltransferase SETD7, Histone H3-K4 methyltransferase SETD7, Lysine N-methyltransferase 7, SET domain-containing protein 7, SET 7/9, H3-K4-HMTase SETD7

Background: Set9 is a histone methyltransferase which specifically methylates lysine 4 of histone H3 being a specific tag for epigenetic transcriptional activation. Further, methylation of histone H3K4 by Set9 precludes deactylation of H3 by the NuRD complex and impairs Suv39h1-mediated methylation of H3K9. Set9 also methylates the tumor suppressor p53 at lysine 372, thereby enchancing its stability. IT contains a SET domain but lacks the pre- and post-SET domains. Anti-Set9 Antibody is ideal for research in Epigenetics, Gene Expression and Chromatin Remodeling.

Gene Name: SETD7

Gene ID: 80854

NCBI Accession: NP_085151

UniProt: Q8WTS6