EZH1 antibody

Catalog No. ABIN6655859

Supplier Product No.: 200-401-h75

This anti-EZH1 antibody is a Rabbit Polyclonal antibody detecting EZH1 in WB. Suitable for Human.

Quick Overview for EZH1 antibody (ABIN6655859)

Target: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EZH1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EZH1 Antibody

Supplier Product No.: 200-401-h75

Supplier: Rockland

Purpose: EZH1 Antibody

Cross-Reactivity (Details): A BLAST analysis was used to suggest cross-reactivity with Anti-EZH1 from human and mouse based on 100 % homology with the immunizing sequence.

Purification: Anti-EZH1 Antibody was purified by Protein G chromatography.

Immunogen: EZH1 Antibody was produced from whole rabbit serum prepared by repeated immunizations at an amino acid sequence located internally within the human EZH1 protein.

Isotype: IgG

Application Details

Application Notes: Optional[Neutralization_Dilution]: 2-4 μg/mL

Comment:

Anti-EZH1 Antibody is tested for use in WB. Expect a band approximately 85kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 0.05 % BSA

Preservative: 0.05 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for EZH1

Target: EZH1 (Enhancer of Zeste Homolog 1 (EZH1))

Alternative Name: EZH1

Background:

Synonyms: KIAA0388, Histone-lysine N-methyltransferase EZH1, 2.1.1.43, ENX-2, Enhancer of zeste homolog 1

Background: Anti-EZH1 Antibody detects human EZH1. EZH1 is a human homolog of the Drosophila gene Enhancer of zeste E(z), a member of the polycomb group of transcriptional repressors. In mice, EZH1 is a regulator of homeotic gene expression implicated in the assembly of repressive protein complexes in chromatin. The strong sequence conservation between species suggests potential role for EZH1 in human development as a transcriptional regulator and as a component of protein complexes that stably maintain heterochromatin. Anti-EZH1 Antibody is ideal for investigators involved in chromatin, NFkappaB, and signaling research.

Gene Name: EZH1

Gene ID: 2145

NCBI Accession: NP_001982

UniProt: Q92800