QKI antibody (AA 1-341)

Catalog No. ABIN6656339

Supplier Product No.: 200-301-w79

This anti-QKI antibody is a Mouse Monoclonal antibody detecting QKI in WB, IHC and ELISA. Suitable for Human.

Quick Overview for QKI antibody (AA 1-341) (ABIN6656339)

Target: QKI (Protein Quaking (QKI))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This QKI antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: S147-6

Product Details anti-QKI Antibody

Binding Specificity: AA 1-341

Supplier Product No.: 200-301-w79

Supplier: Rockland

Purpose: QKI (pan) Antibody

Cross-Reactivity (Details): BLAST analysis suggests that it is 100 % identical to mouse, 99 % identical to rat and 90 % identical to QKI-6, QKI-7 and QKI-7b.

Purification: Anti-QKI (pan) Antibody was purified from concentrated tissue culture supernate by Protein G chromatography.

Sterility: Sterile filtered

Immunogen: Anti-QKI (pan) Antibody was produced by repeated immunization of mice with a fusion protein containing amino acids 1-341 (full length) of human QKI-5.

Isotype: IgG2b

Application Details

Application Notes:

ELISA_Dilution: 1:10,000

Immunohistochemistry_Dilution: User Optimized

Western_Blot_Dilution: 1:1000

Comment:

Anti-QKI (pan) Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~36-38kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.1 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for QKI

Target: QKI (Protein Quaking (QKI))

Alternative Name: QKI

Background:

Synonyms: Protein quaking, Hqk, HqkI, QKI, KH Domain Containing, RNA Binding (QKI)

Background: QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be downregulated in the brain of schizophrenic patients. Anti-QKI (pan) is ideal for research in Neuroscience and Gene Expression.

Gene Name: QKI-5

Gene ID: 9444

UniProt: Q96PU8