DBH antibody (N-Term)

Catalog No. ABIN6657345

Supplier Product No.: 600-601-d28

This Sheep Polyclonal antibody specifically detects DBH in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for DBH antibody (N-Term) (ABIN6657345)

Target: DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This DBH antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DBH Antibody

Binding Specificity: N-Term

Supplier Product No.: 600-601-d28

Supplier: Rockland

Purpose: Dopamine Beta-Hydroxylase Antibody

Cross-Reactivity (Details): Anti-Dopamine beta Hydroxylase Antibody is directed against human Dopamine beta Hydroxylase.

Purification: Anti-Dopamine beta Hydroxylase antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: Anti-Dopamine beta-Hydroxylase Antibody was produced in sheep by repeated immunizations with synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH.

Isotype: IgG

Application Details

Application Notes:

ELISA_Dilution: 1:10,000

Western_Blot_Dilution: 1:1000

Comment:

Anti-Dopamine beta-Hydroxylase Antibody is tested for use in ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 75 kDa in size corresponding to DBH protein in the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for DBH

Target: DBH (Dopamine beta-Hydroxylase (Dopamine beta-Monooxygenase) (DBH))

Alternative Name: Dopamine Beta-Hydroxylase

Background:

Synonyms: Dopamine beta-monooxygenase, DBH

Background: Dopamine beta Hydroxylase Antibody detects DBH which catalyzes the conversion of dopamine to norepinephrine and serves as a marker of noradrenergic cells. DBH antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease and drug abuse. The expression of DBH is also elevated during stress. Anti-Dopamine beta Hydroxylase Antibody is ideal for investigators involved in Neuroscience.

Gene Name: DBH

Gene ID: 1621

UniProt: P09172

Pathways: Carbohydrate Homeostasis