ANGPTL4 antibody (C-Term)

Catalog No. ABIN6657516

Supplier Product No.: 600-401-r03

This Rabbit Polyclonal antibody specifically detects ANGPTL4 in WB. It exhibits reactivity toward Human.

Quick Overview for ANGPTL4 antibody (C-Term) (ABIN6657516)

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANGPTL4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ANGPTL4 Antibody

Binding Specificity: C-Term

Supplier Product No.: 600-401-r03

Supplier: Rockland

Purpose: ANGPTL4 Antibody

Cross-Reactivity (Details): Anti-ANGPTL4 antibody is directed against human ANGPTL4 protein.

Purification: The product was affinity purified from monospecific antiserum by immunoaffinity purification.

Immunogen: ANGPTL4 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a sequence at the C-terminal of human Angptl4.

Isotype: IgG

Application Details

Application Notes: Optional[Neutralization_Dilution]: 0.5 μg/mL

Comment:

Anti-ANGPTL4 is tested for Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~45.2 kDa corresponding to the appropriate cell lysate or extract.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution:

Reconstitution_Buffer: Restore with deionized water (or equivalent)

Reconstitution_Volume: 100 μL

Buffer:

Buffer: 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide

Stabilizer: 5 mg BSA

Preservative: 0.05 mg Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at 4° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for ANGPTL4

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Alternative Name: ANGPTL4

Background:

Synonyms: Angiopoietin-like protein 4,Hepatic fibrinogen/angiopoietin-related protein,

Background: Angiopoietin-related protein 4 (Angptl4) is a protein that in humans is encoded by the ANGPTL4 gene. This gene is a member of the angiopoietin/angiopoietin-like gene family and encodes a glycosylated, secreted protein with a fibrinogen C-terminal domain. This gene is induced under hypoxic conditions in endothelial cells and is the target of peroxisome proliferation activators. By radiation hybrid analysis, Angptl4 gene is mapped to 19p13.3. ANGPTL4 contributed to tumor growth and protected cells from anoikis, a form of programmed cell death induced when contact-dependent cells detach from the surrounding tissue matrix. This antibody is suitable for researchers interested in growth factors and cancer research.

Gene Name: ANGPTL4

Gene ID: 51129

NCBI Accession: NP_001034756

UniProt: Q9BY76

Pathways: Regulation of Lipid Metabolism by PPARalpha