GABRB3 antibody (C-Term)

Catalog No. ABIN6657744

Supplier Product No.: 200-301-f32

This Mouse Monoclonal antibody specifically detects GABRB3 in WB, IHC, IF and FM. It exhibits reactivity toward Mouse.

Quick Overview for GABRB3 antibody (C-Term) (ABIN6657744)

Target: GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This GABRB3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Fluorescence Microscopy (FM)

Clone: N87-25

Product Details anti-GABRB3 Antibody

Binding Specificity: C-Term

Supplier Product No.: 200-301-f32

Supplier: Rockland

Purpose: GABA-A Receptor beta 3 Antibody

Cross-Reactivity (Details): A BLAST analysis was used to suggest cross-reactivity with GABA-A receptor Beta3 from human, mouse, and rat based on 100 % homology with the immunizing sequence.

Purification: Anti-GABA-A receptor Beta 3 Antibody was purified by Protein G chromatography.

Sterility: Sterile filtered

Immunogen: GABA-A Receptor Beta3 Antibody was produced in mice by repeated immunizations with fusion protein corresponding to a near c-terminal region of mouse GABA-A R Beta 3.

Isotype: IgG1

Application Details

Application Notes:

Immunohistochemistry_Dilution: 1:1000

IF_Microscopy_Dilution: 1:100

Western_Blot_Dilution: 1:1000

Comment:

Anti-GABA-A Receptor Beta 3 Antibody is tested for use in WB, IHC, and IF microscopy. Expect a band approximately ~55kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Preservative: 0.09 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for GABRB3

Target: GABRB3 (gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))

Alternative Name: GABA-A Receptor Beta3

Background:

Synonyms: Gabrb3, GABA(A) receptor subunit beta3, Gamma-aminobutyric acid receptor subunit beta-3

Background: The GABA-A receptor is a member of the superfamily of fast acting ligand-gated ion channels. The individual subunits of these receptors have similar sequences and structural features. GABA-A receptors are the major fast inhibitory neurotransmitter gated ion channels in the brain.

Gene Name: Gabrb3

Gene ID: 14402

NCBI Accession: NP_032097

UniProt: P63080

Pathways: Sensory Perception of Sound