Retinoid X Receptor beta antibody

Catalog No. ABIN6657988

Product Details anti-Retinoid X Receptor beta Antibody

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Retinoid X Receptor beta antibody is un-conjugated

Application: Western Blotting (WB)

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Cross reactivity is expected against Rat

Purification: Anti-Retinoid X Receptor beta antibody is directed against RXR-β. Retinoid X Receptor beta antibodies are Protein G purified. This antibody is directed against mouse retinoid x receptor beta protein. . The cross reactivity to from other species has not been determined.

Immunogen:

Immunogen: Anti-Retinoid X Receptor b-Isotype Monoclonal Antibody was produced in mouse by repeated immunizations with Retinoid X Receptor- Synthetic peptide corresponding to amino acid residues from the reported hinge region.

Immunogen Type: Peptide

Clone: 147

Isotype: IgG1

Application Details

Application Notes:

Application Note: Anti-Retinoid X Receptor beta antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 48 kDa in size corresponding to the RXR-β protein in the appropriate cell lysate or extract.

Western Blot Dilution: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Target Details for Retinoid X Receptor beta

Target: Retinoid X Receptor beta (RXRB) (Retinoid X Receptor, beta (RXRB))

Alternative Name: Retinoid X Receptor beta (RXRB Products)

Synonyms: DAUDI6 antibody, H-2RIIBP antibody, NR2B2 antibody, RCoR-1 antibody, RXR-beta antibody, RXRbeta antibody, rxrb antibody, RXRB antibody, nr2b2 antibody, daudi6 antibody, rcor-1 antibody, h-2riibp antibody, NR2B2-A antibody, RXR antibody, RXRA antibody, etID309733.19 antibody, rxre antibody, wu:fb93c09 antibody, AL023085 antibody, Nr2b2 antibody, Rub antibody, rxrd antibody, unp286 antibody, retinoid X receptor beta antibody, retinoid X receptor beta S homeolog antibody, retinoid x receptor, beta a antibody, retinoid x receptor, beta b antibody, RXRB antibody, Rxrb antibody, rxrb.S antibody, rxrb antibody, rxrba antibody, rxrbb antibody

Background:

Synonyms: Nuclear receptor subfamily 2 group B member 2, Retinoid X receptor beta, RXR-β

Background: Retinoid X Receptor beta antibody detects RXR-β. The retinoid X receptors (RXRs) family (RXRα, β and γ), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors. Anti-Retinoid X Receptor beta antibody is ideal for investigators involved in Cancer, Neuroscience, Signal Transduction research.

Gene Name: RXRB

Gene ID: 6257

UniProt: P28702

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway