CACNA1D antibody (Internal Region)

Catalog No. ABIN6658113

Supplier Product No.: 200-301-f09

This Mouse Monoclonal antibody specifically detects CACNA1D in IHC, WB, IP, IF and FM. It exhibits reactivity toward Rat.

Quick Overview for CACNA1D antibody (Internal Region) (ABIN6658113)

Target: CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CACNA1D antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Fluorescence Microscopy (FM)

Clone: S48

Product Details anti-CACNA1D Antibody

Binding Specificity: Internal Region

Supplier Product No.: 200-301-f09

Supplier: Rockland

Purpose: Cav1.3 Antibody

Purification: Anti-Cav1.3 Antibody was purified by Protein G chromatography.

Sterility: Sterile filtered

Immunogen: Cav1.3 Antibody was produced in mice by repeated immunizations with a fusion protein corresponding to an internal region of rat Cav1.3.

Isotype: IgG2a kappa

Application Details

Application Notes:

Immunoprecipitation_Dilution: User Optimized

Immunohistochemistry_Dilution: 0.1-1.0 μg/mL

IF_Microscopy_Dilution: 1.0-10 μg/mL

Western_Blot_Dilution: 1-10 μg/mL

Comment:

Anti-Cav1.3 Antibody was tested in WB, IP, IHC, and IF microscopy. Expect a band approximately ~250kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for CACNA1D

Target: CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))

Alternative Name: Cav1.3

Background:

Synonyms: CACH3, CACN4, CACNA 1D, CACNL1A2, voltage dependent L type calcium channel subunit alpha 1D, Calcium channel, L type, alpha-1 polypeptide, isoform 2, Rat brain class D

Background: Specifically, Cav1.3, also known as the calcium channel, voltage-dependent, L type, alpha 1D subunit (CACNA1D), is a human gene. Cav1.3 subunits are primarily expressed in neurons and neuroendocine cells. Some studies suggest however that Cav1.3 is also found in the atria, and may figure prominently in atrial arrhythmias. Cav1.3 also carries the primary sensory receptors of the mammalian cochlea, and are also expressed in the electromotile outer hair cells.

Gene Name: Cacna1d

Gene ID: 29716

NCBI Accession: NP_058994

UniProt: P27732

Pathways: Sensory Perception of Sound