SNAP25 antibody (C-Term)

Catalog No. ABIN6658261

Supplier Product No.: 612-401-e31

The Rabbit Polyclonal anti-SNAP25 antibody has been validated for WB. It is suitable to detect SNAP25 in samples from Rat.

Quick Overview for SNAP25 antibody (C-Term) (ABIN6658261)

Target: SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAP25 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SNAP25 Antibody

Binding Specificity: C-Term

Supplier Product No.: 612-401-e31

Supplier: Rockland

Purpose: SNAP25 Antibody

Cross-Reactivity (Details): SNAP25 antibody is affinity purified from monospecific antiserum by immunoaffinity purification.

Purification: Anti-SNAP25 antibody is directed against rat SNAP25.

Immunogen: Anti-SNAP25 Antibody was produced by repeated immunizations with synthetic peptide corresponding to amino acid residues from the C-terminal region of SNAP25 protein.

Isotype: IgG

Application Details

Application Notes: Optional[Neutralization_Dilution]: 1:1000

Comment:

Anti-SNAP 25 antibody is tested for use in Western Blots. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 25 kDa in size corresponding to SNAP25 protein in the appropriate cell lysate or extracts.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer:

Buffer: 0.01 M HEPES, 0.15 M Sodium Chloride, pH 7.5

Stabilizer: 0.1 mg/mL Bovine Serum Albumin (BSA) - IgG and Protease free, 50 % (v/v) Glycerol

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details for SNAP25

Target: SNAP25 (Synaptosomal-Associated Protein, 25kDa (SNAP25))

Alternative Name: SNAP25

Background:

Synonyms: Synaptosomal-associated protein 25, Super protein, SUP, Synaptosomal-associated 25 kDa protein

Background: SNAP25 antibody detects synaptosomal associated protein of 25 kDa, which is a presynaptic plasma membrane protein widely distributed throughout the brain. SNAP25 is involved in the regulation of neurotransmitter release, and decreased levels of SNAP25 have been found in the brains of patients with Down Syndrome and Alzheimer's Disease. In addition, a significant reduction in the hippocampal expression of SNAP25 has also been found in patients with Schizophrenia. Anti-SNAP25 Antibody is ideal for investigators involved in Neuroscience, and Signal Transduction research.

Gene Name: SNAP25

Gene ID: 25012

UniProt: P60881

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport