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VCAM1 antibody (AA 640-739)

VCAM1 Reactivity: Human, Mouse, Rat FACS, WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN668080
  • Target See all VCAM1 Antibodies
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Binding Specificity
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 640-739
    Reactivity
    • 115
    • 68
    • 24
    • 10
    • 8
    • 6
    • 6
    • 3
    • 3
    Human, Mouse, Rat
    Host
    • 75
    • 69
    • 34
    • 5
    • 1
    • 1
    Rabbit
    Clonality
    • 120
    • 63
    • 1
    Polyclonal
    Conjugate
    • 91
    • 26
    • 25
    • 10
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This VCAM1 antibody is un-conjugated
    Application
    • 85
    • 80
    • 56
    • 39
    • 34
    • 27
    • 16
    • 15
    • 14
    • 8
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from mouse VCAM-1
    Isotype
    IgG
    Top Product
    Discover our top product VCAM1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Liu, Davidson, Yue, Belcik, Xie, Inaba, McCarty, Tormoen, Zhao, Ruggeri, Kaufmann, Lindner: "Molecular imaging of inflammation and platelet adhesion in advanced atherosclerosis effects of antioxidant therapy with NADPH oxidase inhibition." in: Circulation. Cardiovascular imaging, Vol. 6, Issue 1, pp. 74-82, (2013) (PubMed).

  • Target
    VCAM1 (Vascular Cell Adhesion Molecule 1 (VCAM1))
    Alternative Name
    VCAM-1 (VCAM1 Products)
    Background

    Synonyms: CD106, Vcam-1, Vascular cell adhesion protein 1, V-CAM 1, Vcam1

    Background: Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.

    Gene ID
    22329
    UniProt
    P29533
    Pathways
    Carbohydrate Homeostasis
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