DISC1 antibody (AA 761-832) (Biotin)

Catalog No. ABIN668543

The Rabbit Polyclonal anti-DISC1 antibody has been validated for ELISA, IHC (p), IHC (fro). It is suitable to detect DISC1 in samples from Human.

Quick Overview for DISC1 antibody (AA 761-832) (Biotin) (ABIN668543)

Target: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DISC1 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-DISC1 Antibody (Biotin)

Binding Specificity: AA 761-832

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DISC1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for DISC1

Target: DISC1 (Disrupted in Schizophrenia 1 (DISC1))

Alternative Name: DISC1

Background:

Synonyms: disrupted in schizophrenia1, C1orf136, KIAA0457, RP4-730B13.1, SCZD9, DISC1, DISC1_HUMAN.

Background: This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1,11)(q42.1,q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].

Gene ID: 27185

UniProt: Q9NRI5

Pathways: Regulation of Cell Size