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tau antibody (PerCP)

Reactivity: Human, Mouse WB, ELISA Host: Rabbit Polyclonal PerCP
Catalog No. ABIN6698780
  • Target See all tau Antibodies
    tau (tau Protein)
    Reactivity
    • 524
    • 500
    • 498
    • 40
    • 28
    • 27
    • 18
    • 6
    • 3
    • 2
    • 1
    • 1
    Human, Mouse
    Host
    • 629
    • 35
    • 2
    • 1
    Rabbit
    Clonality
    • 604
    • 62
    • 1
    Polyclonal
    Conjugate
    • 208
    • 40
    • 34
    • 33
    • 33
    • 33
    • 32
    • 32
    • 32
    • 30
    • 24
    • 24
    • 24
    • 24
    • 24
    • 13
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    This tau antibody is conjugated to PerCP
    Application
    • 547
    • 272
    • 263
    • 204
    • 92
    • 85
    • 67
    • 59
    • 53
    • 36
    • 34
    • 16
    • 12
    • 12
    • 12
    • 9
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA
    Specificity
    Detects ~45.8kda.
    Purification
    Protein A Purified
    Immunogen
    Synthetic peptide from the full length of Human Tau
    Top Product
    Discover our top product tau Primary Antibody
  • Application Notes
    • WB (1:1000)
    • optimal dilutions for assays should be determined by the user.
    • optimal dilutions for assays should be determined by the user.
    Comment

    A 1:1000 dilution of ABIN6698780 was sufficient for detection of Tau in 10 μg of human SH-SY5Y cell lysate cell lysates by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.09 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
  • Target
    tau (tau Protein)
    Alternative Name
    Tau (tau Products)
    Synonyms
    DDPAC antibody, FTDP-17 antibody, MAPTL antibody, MSTD antibody, MTBT1 antibody, MTBT2 antibody, PPND antibody, TAU antibody, tau antibody, PHF-tau antibody, microtubule associated protein tau antibody, MAPT antibody
    Background
    Alzheimer's Disease (AD) is the most common neurodegenerative disease, affecting 10 % of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3). There are six isoforms of tau in the adult human brain: three with four repeat units (4R) and three with three repeat units (3R) (4). K18 is a truncated form of human tau containing only the 4 microtubule binding repeats (5). P301L (PL) is a mutation where proline is replaced by leucine at codon 301 of tau, and has been linked to frontotemporal dementia (6).
    Gene ID
    4137
    UniProt
    P10636
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