Nuclear Stain of Multiple Gene Products Including Nup62, Nup133 antibody

Catalog No. ABIN6699198

Supplier Product No.: 900-301-d98

This Mouse Monoclonal antibody specifically detects in IF and FM. It exhibits reactivity toward Saccharomyces cerevisiae.

Quick Overview for Nuclear Stain of Multiple Gene Products Including Nup62, Nup133 antibody (ABIN6699198)

Target: Nuclear Stain of Multiple Gene Products Including Nup62, Nup133

Reactivity: Saccharomyces cerevisiae

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Immunofluorescence (IF), Fluorescence Microscopy (FM)

Clone: 39C7

Product Details

Supplier Product No.: 900-301-d98

Supplier: Rockland

Purpose: Nuclear Pore Complex Antibody

Cross-Reactivity (Details): Anti-Nuclear Pore Complex antibody is directed against Nuclear Pore Complex proteins.

Purification: The antibody is protein G purified from concentrated clarified cell culture supernate.

Immunogen: Anti-Nuclear Pore Complex Antibody (Monoclonal) was produced by repeated immunizations with yeast nuclear preparations.

Isotype: IgG1

Application Details

Application Notes:

IF_Microscopy_Dilution: 1:50-100

Other: User Optimized

Comment:

Anti-Nuclear Pore Complex Antibody is tested for use in ICC/IF. Specific conditions for reactivity should be optimized by the end user

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Optional[Buffer]: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 ,0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Expiry Date: 12 months

Target Details

Target: Nuclear Stain of Multiple Gene Products Including Nup62, Nup133

Background:

Synonyms: mouse anti-Nuclear Pore Complex Antibody, NPC, NUP62, NUP, NUP133

Background: Nuclear Pore Complex Antibodydetects Nuclear Pore Complex proteins. The nuclear pore complex (NPC) is a very large structure made up of at least 50 different proteins that span the double membrane of the nuclear envelope functioning as a gateway for macromolecular traffic between the cytoplasm and the nucleus. Discrete nuclear pore complex proteins or nucleoporins such as NUP98, NUP180 and p62 have been implicated in autoimmune disease and cancer. Patients with primary biliary cirrhosis (PBC) frequently produce autoantibodies against p62 and NUP180 while NUP98 translocations have been found in patients with acute myelogenous leukemia (AML). Anti-Nuclear Pore Complex Antibody is ideal for investigators involved in Cancer and Immunology Research.

Gene Name: Nuclear stain of multiple gene products including Nup62, Nup133