CAMK2A antibody (AA 401-478)

Catalog No. ABIN670176

The Rabbit Polyclonal anti-CAMK2A antibody (ABIN670176) specifically detects CAMK2A in WB, IHC (p), FACS, IHC (fro), IF (cc) and IF (p). The antibody is reactive with Human samples.

Quick Overview for CAMK2A antibody (AA 401-478) (ABIN670176)

Target: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAMK2A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CAMK2A Antibody

Binding Specificity: AA 401-478

Purpose: CaMK2 alpha Polyclonal Antibody

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Chicken,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CaMK2a

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CAMK2A

Target: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Alternative Name: CaMK2 alpha

Background:

Synonyms: alpha CaMKII, Calcium / Calmodulin Dependent Protein Kinase II G, Calcium calmodulin dependent protein kinase CaM kinase II alpha, Calcium calmodulin dependent protein kinase II alpha-B subunit, Calcium calmodulin dependent protein kinase II, Calcium/calmodulin dependent protein kinase II alpha, Calcium/calmodulin-dependent protein kinase CaM kinase II alpha, Calcium/calmodulin-dependent protein kinase II alpha, Calcium/calmodulin-dependent protein kinase II-alpha, Calcium/calmodulin-dependent protein kinase type II subunit alpha, Calcium/calmodulin-dependent protein kinase type IIA, CaM kinase II alpha chain, CaM kinase II alpha subunit, CaM kinase II subunit alpha, CAM2, CaMK II alpha subunit, CaMK-II subunit alpha, CAMK2A, CAMKA, CAMKB, CaMKII, CaMK 2a, CaMK2a, KCC2A_HUMAN.

Background: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008].

Gene ID: 815

Pathways: WNT Signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction