SULT1E1 antibody (AA 51-145)

Catalog No. ABIN671106

Product Details anti-SULT1E1 Antibody

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Binding Specificity: AA 51-145

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Estrogen Sulfotranferase

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SULT1E1

Target: SULT1E1 (Sulfotransferase Family 1E Member 1 (SULT1E1))

Alternative Name: Estrogen Sulfotransferase

Background:

Synonyms: EST, STE, EST-1, ST1E1, Estrogen sulfotransferase, Sulfotransferase 1E1, Sulfotransferase, estrogen-preferring, SULT1E1

Background: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of estradiol and estrone. May play a role in the regulation of estrogen receptor activity by metabolizing free estradiol. Maximally sulfates beta-estradiol and estrone at concentrations of 2 nM. Also sulfates dehydroepiandrosterone, pregnenolone, ethinylestradiol, equalenin, diethylstilbesterol and 1-naphthol, at significantly higher concentrations, however, cortisol, testosterone and dopamine are not sulfated.

Gene ID: 6783

UniProt: P49888

Pathways: Steroid Hormone Biosynthesis