MVP antibody (AA 88-180)

Catalog No. ABIN671586

This anti-MVP antibody is a Rabbit Polyclonal antibody detecting MVP in FACS, ELISA, IHC (p), IHC (fro), IF (cc) and IF (p). Suitable for Human and Zebrafish (Danio rerio). This Primary Antibody has been cited in 3+ publications.

Quick Overview for MVP antibody (AA 88-180) (ABIN671586)

Target: MVP (Major Vault Protein (MVP))

Reactivity: Human, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MVP antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-MVP Antibody

Binding Specificity: AA 88-180

Cross-Reactivity: Human, Zebrafish (Danio rerio)

Cross-Reactivity (Details): Zebrafish

Predicted Reactivity: Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LRP

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-MVP antibody (ABIN671586)

Peng, Feng, Yuan, Benhabbour, Mumper: "Development of a novel orthotopic non-small cell lung cancer model and therapeutic benefit of 2'-(2-bromohexadecanoyl)-docetaxel conjugate nanoparticles." in: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 7, pp. 1497-506, (2014) (PubMed).

Pan, Lin, Ma, Shen, Schachner: "Major vault protein promotes locomotor recovery and regeneration after spinal cord injury in adult zebrafish." in: The European journal of neuroscience, Vol. 37, Issue 2, pp. 203-11, (2013) (PubMed).

Hu, Peng, Li: "The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 28, pp. 144, (2009) (PubMed).

Target Details for MVP

Target: MVP (Major Vault Protein (MVP))

Alternative Name: LRP

Background:

Synonyms: LRP, VAULT1, Major vault protein, MVP, Lung resistance-related protein

Background: Required for normal vault structure. Vaults are multi-subunit structures that may act as scaffolds for proteins involved in signal transduction. Vaults may also play a role in nucleo-cytoplasmic transport. Down-regulates INFG-mediated STAT1 signaling and subsequent activation of JAK. Down-regulates SRC activity and signaling through MAP kinases.

Gene ID: 9961

UniProt: Q14764