TYRO3 antibody (AA 41-147) (DyLight 550)

Catalog No. ABIN7354565

The Rabbit Polyclonal anti-TYRO3 antibody has been validated for FACS. It is suitable to detect TYRO3 in samples from Human.

Quick Overview for TYRO3 antibody (AA 41-147) (DyLight 550) (ABIN7354565)

Target: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TYRO3 antibody is conjugated to DyLight 550

Application: Flow Cytometry (FACS)

Product Details anti-TYRO3 Antibody (DyLight 550)

Binding Specificity: AA 41-147

Purpose: Anti-Human TYRO3 DyLight® 550 conjugated Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Characteristics: Anti-Human TYRO3 DyLight® 550 conjugated Antibody -Dyl550. Tested in Flow Cytometry applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human TYRO3 recombinant protein (Position: A41-D147).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells1. "Entrez Gene: TYRO3 TYRO3 protein tyrosine kinase". 2. Polvi A, Armstrong E, Lai C, Lemke G, Huebner K, Spritz RA, Guida LC, Nicholls RD, Alitalo K (1994). "The human TYRO3 gene and pseudogene are located in chromosome 15q14-q25". Gene. 134 (2): 289-93.

Comment:

Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Target Details for TYRO3

Target: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Alternative Name: TYRO3

Background:

Synonyms: Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase BYK, Tyrosine-protein kinase DTK, Tyrosine-protein kinase RSE, Tyrosine-protein kinase SKY, Tyrosine-protein kinase TIF, TYRO3, BYK, DTK, RSE, SKY, TIF

Tissue Specificity: Abundant in the brain and lower levels in other tissues.

Background: Tyrosine-protein kinase receptor TYRO3 is an enzyme that in humans is encoded by the TYRO3 gene. The gene is part of a 3-member transmembrane receptor kinase receptor family with a processed pseudogene distal on chromosome 15. The encoded protein is activated by the products of the growth arrest-specific gene 6 and protein S genes and is involved in controlling cell survival and proliferation, spermatogenesis, immunoregulation and phagocytosis. The encoded protein has also been identified as a cell entry factor for Ebola and Marburg viruses.

Molecular Weight: 39 kDa

Gene ID: 7301

UniProt: Q06418

Pathways: RTK Signaling